His talents for many instruments came in handy when playing Blind Lemon Jefferson in the movie Leadbelly.
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Cheech and Chong parodied Jefferson as "Blind Melon Chitlin'" on their self-titled 1971 album Cheech and Chong (album), their 1985 album Get Out of My Room, and in a stage routine that can be seen in their 1983 movie Still Smokin'.
Blind Lemon Jefferson, an influential blues musician, was born and is buried in Wortham.
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Ari Eisinger is a guitarist and singer from Pennsylvania, most noted as a proponent of Piedmont blues guitar from the 1920s-1930s, and as a significant authority on the music of the Rev. Gary Davis, Blind Blake, Blind Lemon Jefferson, Blind Boy Fuller, and Josh White amongst others.
According to Greene's fellow musician and musical contemporary, Walter Davis, both Greene and Davis advanced their prowess on guitar by observing itinerant country blues artist Blind Lemon Jefferson, who played on the streets of Johnson City, Tennessee, during the early 1920s.
His earliest influences were popular blues artists of the day such as Bessie Smith, Blind Lemon Jefferson and Leroy Carr, together with country musicians including Jimmie Rodgers and Bob Wills.
Starting in 2006, the first inductees chosen by the Paramount GIG ('Grooves In Grafton') organization, in Grafton, were Charley Patton, Ma Rainey, Blind Lemon Jefferson, Skip James, Thomas Dorsey, and Henry Townsend.