He was appointed to the IRA's Internal Security Unit and liaised between Northern Command and rural units in Tyrone and Armagh.
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Against the wishes of the IRA Army Council, on 27 October 1980, Hughes along with six other republican prisoners, including Tom McFeely, John Nixon, Sean McKenna, Tommy McKearney and Raymond McCartney, refused food and started a hunger strike.
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He was a cousin of Charles Hughes, who was the OC of D Company in the Provisional IRA Belfast Brigade during the Falls Curfew, and was shot and killed in March 1971 by the Official Irish Republican Army during the feud between the Provisional and Official IRA.
Howard Hughes | Langston Hughes | Ted Hughes | Charles Evans Hughes | Brendan Behan | Glenn Hughes | Brendan Fraser | Rhys Hughes | John Hughes | Thomas Hughes | Sarah Hughes | Hughes Aircraft Company | Gary Hughes | Billy Hughes | Baker Hughes | John Hughes (filmmaker) | Brendan Perry | Brendan Byrne | Adam Hughes | Mark Hughes | Emlyn Hughes | Wendy Hughes | Simon Hughes | Brendan O'Carroll | Brendan Benson | Phil Hughes | Hugh Price Hughes | Hughes Helicopters | Hughes | David Hughes |
McIntyre was involved with the Boston College oral history project on the Irish troubles, conducting interviews with former IRA members such as Brendan Hughes and Dolours Price and loyalists such as David Ervine.
During Gerry Adams' initial career in the republican movement he took much of his direction from Brendan Hughes and Bell.