John Brisker (born 1947, Detroit, Michigan), an American professional basketball player
Boruch Ber Leibowitz, main student of Rabbi Chaim Brisker famed for his Talmudic lectures
However, as Rabbi Joseph Soloveitchik suggested in his eulogy for the Brisker Rov, the full, true "Brisk approach" as we know it today was not developed until Rabbi Chaim Soloveitchik had been rabbi of Brisk for many years.
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The Brisker method, or Brisker derech, is a reductionistic approach to Talmud study innovated by Rabbi Chaim Soloveitchik of Brisk, as opposed to the traditional approach which was rather holistic.