Notable former medical staff include Geoffrey Tovey, serologist and founder of the UK Transplant Service.
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In 1904, Sir George White, who gave Bristol its first electric tramway service and established what was to become the Bristol Aeroplane Company, saved the hospital from a major financial crisis, and later masterminded the construction of the BRI Edward VII Memorial Wing, designed by Charles Holden.
After the Henleys died the Red Lodge was leased to tenants practising medicine working at the Bristol Royal Infirmary, including James Cowles Pritchard who wrote Researches into the Physical History of Man, and Francis Cheyne Bowles and Richard Smith, who used the Great Oak Room as a dissection theatre.
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Between 1922-27, he attended medical schools at the Bristol Royal Infirmary, and St Mary's Hospital, London, London, achieving MRCS and LRCP.
Clinical governance became important in health care after the Bristol heart scandal in 1995, during which anaesthetist Dr Stephen Bolsin exposed the high mortality rate for paediatric cardiac surgery at the Bristol Royal Infirmary.