In 1981 she made her operatic debut in Florence as Giulietta in Bellini's I Capuleti e i Montecchi and rose to prominence following her successful debut at La Scala in 1982 when at very short notice she replaced Montserrat Caballé in the title role of Donizetti's Anna Bolena.
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That same year she won the first prize in the "New Voices for Opera" competition dedicated to Maria Callas.
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Her Metropolitan Opera debut in 1986 as another 'Juliette', this time in Gounod's Roméo et Juliette.
Soloists who have performed with the orchestra include Cecilia Gasdia, Ghena Dimitrova, Miriam Gauci, Joseph Calleja, Andrea Bocelli, José Carreras, Kate Aldrich, Daniela Dessi, and Lydia Caruana.
As a composer, arranger and conductor he has collaborated with many Artists such as Andrea Bocelli, Sara Brightman, Gustav Kuhn, Cecilia Gasdia, Anna Caterina Antonacci, Valeria Esposito, Andrea Griminelli, Valeria Moriconi, Federico Mondelci, Enrico Dindo, Elena Zaniboni, Danilo Rossi, Giorgio Zagnoni.
Cecilia Bartoli | Accademia Nazionale di Santa Cecilia | Saint Cecilia | Cecilia | Cecilia Gasdia | Santa Cecilia | Cecilia Valdés | Cecilia Frode | Cecilia Cheung | St. Cecilia's Abbey | Orchestra dell'Accademia Nazionale di Santa Cecilia | Lydia Cecilia Hill | Cecilia Vicuña | Cecilia Vennersten | Cecilia Tait | Cecilia Roth | Cecilia Payne-Gaposchkin | Cecilia Morel | Cecilia Malmström | Cecilia Frank | Cecilia Colledge | Cécilia Attias | St Cecilia's Convent Secondary School | St. Cecilia's Convent | St. Cecilia's Abbey, Ryde | St Cecilia's Abbey, Ryde | St. Cecilia, or the Power of Music | St. Cecilia Cathedral | St. Cecilia | Princess Cecilia of Sweden |