DeLisi is recipient of numerous awards including the Presidential Citizens Medal, awarded to him by President Clinton for his seminal role in initiating the Human Genome Project.
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Prior to moving to Boston University, he was Professor and Chair of Biomathematical Sciences and Professor of Molecular Biology at the Mount Sinai School of Medicine (1987–1989), Director of the United States Department of Energy's Health and Environmental Research Programs (1985–1987), Section Chief at National Institutes of Health (1975–1985), and Theoretical Division Staff Scientist at Los Alamos National Laboratory (1972–1975).
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Commemorating the significance of the Human Genome Project, the DOE installed a bronze plaque outside room F-202 at its Germantown, Maryland facility.
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In 1985, as Director of the U.S. Department of Energy’s (DOE) Health and Environmental Research Programs, DeLisi and his advisors proposed, planned and defended before the White House Office of Management and Budget and the Congress, the Human Genome Project.
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