He began research into a hereditary disease of the kidneys which was greatly expanded by his pupil Oliver Wrong and named Dent's disease.
Dent's disease was first described by Charles Enrique Dent and M. Friedman in 1964, when they reported two unrelated British boys with rickets associated with renal tubular damage characterized by hypercalciuria, hyperphosphaturia, proteinuria, and aminoaciduria.
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