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He was the son of Charles Harrison Tweed, the general counsel for the Central Pacific Railroad, Chesapeake and Ohio and other affiliated railroad corporations, and his wife, (Helen) Minerva Evarts.
The Richmond Vampire is an urban legend that began soon after a collapse on the Chesapeake and Ohio Railroad's Church Hill Tunnel at Church Hill, a district of Richmond, Virginia, which buried several workers alive on October 2, 1925.