X chromosome | Y chromosome | Philadelphia chromosome | polytene chromosome | Human Y-chromosome DNA haplogroup | An inversion loop in the A arm of a chromosome from an ''Axarus |
The TRPV4 (transient receptor potential vanilloid 4) gene, located on chromosome 12, encodes for a protein that serves as an ion channel, typically found in the plasma membrane and is permeable to Ca2+.
It is shuttled from chromosome 12 to chromosome 2 by the Suz-Twelve protein.
Immunodeficiency with hyper IgM type 2 is caused by a mutation in the Activation-Induced Cytidine Deaminase (AICDA) gene, which is located on the short arm of chromosome 12.
Immunodeficiency with hyper IgM type 5 is caused by a mutation in the Uracil-DNA glycosylase (UNG) gene, which, like AICDA, is located on chromosome 12.