Females are not affected by the condition, however due to linkage of heredity with the X chromosome, they are thought to be genetic carriers.
Dr Jozef Gécz is a senior researcher at The University of Adelaide studying the various mutations of a small part of the X chromosome that lead to mental retardation.
But unlike other tragelaphids, the X chromosome and Y chromosome are compound and fused with autosomes from ancestors having a greater chromosome number.
The MAGEA genes are clustered at chromosomal location Xq28.
It was first noted that the X chromosome was special in 1890 by Hermann Henking in Leipzig.
X chromosome | Y chromosome | Philadelphia chromosome | polytene chromosome | Human Y-chromosome DNA haplogroup | An inversion loop in the A arm of a chromosome from an ''Axarus |
Differences between the X chromosome and Y chromosome versions of the amelogenin gene (AMELX and AMELY respectively) enable it to be used in sex determination of unknown human samples.
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The amelogenin gene has been most widely studied in humans, where it is a single copy gene, located on the X and Y chromosomes at Xp22.1-Xp22.3 and Yp 11.2 5.
Xist (X-inactive-specific transcript) is a long ncRNA gene on the X chromosome of the placental mammals that acts as major effector of the X chromosome inactivation process forming Barr bodies.
PCDH11X located on the X chromosome is common, in both sexes, to humans and our nearest relative, the chimpanzee; however, PCDH11Y located on the Y chromosome, is unique to men.
XLA is caused by a mutation on the X chromosome of a single gene identified in 1993 which produces an enzyme known as Bruton's tyrosine kinase, or Btk.
One study showed weak linkage to the Xq28 region, whereas a second in 1999 studying Canadian material consisting of 52 pairs of gay brothers found no statistically significant linkage in alleles and haplotypes and concluded against an X-linked male homosexuality gene.
This gene encodes a DEAD box protein, and it has a homolog on the X chromosome (DDX3X).
Duchenne muscular dystrophy, a severe recessive X-chromosome linked form of muscular dystrophy
A new colleague at the City of Hope and ultimately a lifelong friend, Susumu Ohno had recently demonstrated that the histologically observable Barr body present in the nuclei of mammalian female cells was a hyperchromatic X chromosome.
X-inactivation, also called lyonization, a process by which one of the two copies of the x chromosome present in female mammals is inactivated
Some patients with SFMS have been founded to have a mutation of the gene in the ATRX on the X chromosome, also known as the Xq13 location.
He also discovered in 1956 that the Barr body of mammalian female nuclei was in fact a condensed X chromosome.