Clement Comer Clay (1789–1866), Governor of Alabama 1835–1837, and U.S. Senator from Alabama 1837–1841
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Prominent attendees included John C. Calhoun, Clement C. Clay, Sr., John Bell, William Gwin, and Edmund P. Gaines, but it was James Gadsden of South Carolina who was influential in the convention’s recommending a southern route for the proposed railroad, beginning in Texas and ending in San Diego or Mazatlán.
Clement Claiborne Clay (1816–1882), son of Clement Comer Clay; U.S. Senator from Alabama 1853–1861, and Confederate States senator from Alabama 1861–1863