The Astor Expedition of 1810-1812, was the next overland expedition from St. Louis, Missouri to the mouth of the Columbia River after the Corps of Discovery, led by Lewis and Clark.
Following an arduous trek through the Bitterroot Mountains, suffering through a mid-September snowstorm and near starvation, the Corps of Discovery expedition camped with the Nez Perce tribe on the Weippe Prairie outside of present-day Weippe in 1805.
In 2004–2005 the mint issued four commemorative nickel five cent pieces in the Westward Journey Nickel Series, celebrating the 200th anniversaries of the Louisiana Purchase and the Corps of Discovery.
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George Drouillard (Shawnee) (1773-1810) was a civilian interpreter, scout, hunter, and cartographer, hired at the age of 20 for Lewis and Clark's Voyage of Discovery to explore the territory of the Louisiana Purchase in 1804-1806, in search of a water route to the Pacific Ocean.