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3 unusual facts about Corticosteroid


Lewis Hastings Sarett

He invented a Process of Treating Pregnene Compounds Cortisone, Patent Number 2,462,133.

Mollie Sugden

In an unsuccessful revival of The Liver Birds (1996), Sugden reprised her role as Mrs Hutchinson, despite being on steroids at the time owing to her suffering from polymyalgia.

Post-traumatic epilepsy

Corticosteroids have also been investigated for the prevention of PTE, but clinical trials revealed that the drugs did not reduce late PTS and were actually linked to an increase in the number of early PTS.


Etomidate

Etomidate suppresses corticosteroid synthesis in the adrenal cortex by reversibly inhibiting 11-beta-hydroxylase, an enzyme important in adrenal steroid production; it leads to primary adrenal suppression.

Management of Crohn's disease

Budesonide is an oral corticosteroid with limited absorption and high level of first-pass metabolism, meaning that less quantities of steroid enter into the bloodstream.

Nasal spray

Corticosteroid nasal sprays such as Nasonex (Mometasone furoate) and Rhinocort (Budesonide) can be used to relieve the symptoms of sinusitis, hay fever, allergic rhinitis and non-allergic (perennial) rhinitis.


see also