He is grandson of the famous director Luigi Comencini, after several experiences as assistant director of Antonio Albanese, Luigi Comencini and Cristina Comencini, debut as film director in 2001 with the comedy Se fossi in te.
Simona Lisi works also as an actress: in 2005 she played the mother of the leading character (played by Giovanna Mezzogiorno) in the Academy Award-nominated La bestia nel cuore (The Beast in the Heart), directed by Cristina Comencini.
Cristina Fernández de Kirchner | Luigi Comencini | María Cristina Kiehr | Giuseppe Di Cristina | Cristina Teuscher | Cristina Comencini | Teresa Cristina of the Two Sicilies | Maria Cristina of Savoy | Cristina Vergano | Cristina Hoyos | Justice for All with Judge Cristina Pérez | Infanta Maria Cristina of Spain | Cristina López | Cristina Donà | Cristina D'Avena | Cristina Alberdi | Spanish cruiser Reina Cristina | Santa Cristina | ''Reina Cristina'' | Princess Maria Cristina of Savoy-Aosta | Princess Maria Cristina of Savoy | Maria Cristina of Naples and Sicily | Maria Cristina Giongo | Maria Cristina Giai Pron | Maria Cristina Bridge | Infanta Cristina, Duchess of Palma de Mallorca | Cristina Trivulzio Belgiojoso | Cristina Rus | Cristina Pato | Cristina Pantoja-Hidalgo |