X-Nico

6 unusual facts about DQ2


Dermatitis herpetiformis

It is most common in patients of northern European ancestry, and is associated with the HLA-DQ2 haplotype along with celiac disease and gluten sensitivity.

HLA DR3-DQ2

HLA DR3-DQ2 is the serotypic representation of a HLA-DRB1:DQA1:DQB1

With coeliac disease risk is increased with the consumption of Triticeae glutens, and this also increases risk in juvenile diabetes whereas other cereals also appear to play a role.

The DR3-DQ2 haplotype is notable because of the very strong linkage between genes that extends into the HLA-A, -B and -C regions of the HLA gene complex in northern and northwestern Europe.

HLA-DQ7

DQA1*0505, without DQ2, is found in a small percentage of coeliac disease (without DQ2 or DQ8).

HLA-DQ9

The recognition of DQB1*0303 by DQ9 and or DQ3 is poorest, DQ2 which recognizes a different DQB1 subgroup recognizes DQB1*0303 as efficiently as DQ3.


Similar

HLA-DQ2 | DQ2 |


see also