Although widely regarded today as a weed, this species was once part of the eastern agricultural complex of prehistoric North America, and was a fully domesticated pseudocereal crop, similar to the closely related quinoa C.
The Eastern Agricultural Complex describes the agricultural practices of the pre-historic Eastern Woodland Native Americans in the eastern United States and the First Nations in Canada.
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The tiny seeds are edible, and this plant was part of the Eastern Agricultural Complex of cultivated plants used in Pre-Columbian times by Native Americans.