After the resignation of the last shōgun the Meiji government took control over the medical institutions of the Tokugawa regime and assigned Sagara Chian and Iwasa Jun from Echizen to draft a programm for the new system of medical care and education.
He was raised in Echizen Province, which was in the southern portion of present day Fukui Prefecture.
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suggests he was born in Echizen province, but there are other plausible locations, including Hagi, Nagato province.
In 1575, he aided in Nobunaga's assaults on the Ikkō-ikki of Echizen Province, and fought the Saika Ikki two years later, leading Nobunaga's army alongside Hashiba Hideyoshi and Sakuma Nobumori.
Along with Maeda Toshiie and Fuwa Mitsuharu, Narimasa was charged with keeping the peace and suppressing the Ikkō-ikki in Echizen Province.