In 1934, Lamb turned from corporate to labor law after workers at the Auto-Lite auto parts manufacturer asked him to represent them during the Auto-Lite Strike.
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In his later years, Lamb was a trustee of the United Nations Association chapter in the United States, and participated in peace and civil rights demonstrations in the 1960s.
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He was also a trustee of the Fund for the Republic, a civil rights organization which was absorbed by the Center for the Study of Democratic Institutions in 1979.
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George Hamilton Lamb and his twin sister Florence were born in Epsom, a suburb of Bendigo, to William Edward Lamb (an auctioneer and schoolteacher) and his wife, Sarah Victoria Lamb (née Irwin), also a teacher.