This gene belongs to the AFF family of genes which currently has four members: AFF1/AF4, AFF2/FMR2, AFF3/LAF4 and AFF4/AF5q31.
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The most common mutation giving rise to this syndrome is a triplet expansion of CCG in the 5' untranslated region which leads to a silencing of the gene.
ICD-10 Chapter V: Mental and behavioural disorders | Diagnostic and Statistical Manual of Mental Disorders | National Institute of Mental Health | National Mental Health Act | Camarillo State Mental Hospital | Not Fragile | mental | Fragile (film) | World Federation for Mental Health | Woodhull Medical and Mental Health Center | Souris Valley Mental Health Hospital | New York City Department of Health and Mental Hygiene | National Alliance on Mental Illness | Loaded Mental Cannon | Fragile X syndrome | Fragile | Elgin Mental Health Center | Centre for Addiction and Mental Health | Bazelon Center for Mental Health Law | Alaska Mental Health Enabling Act | The Fragile Art of Existence | Thank God For Mental Illness | Self-help groups for mental health | Royal Ottawa Mental Health Centre | Retardation | Psychomotor retardation | President's Commission on Mental Health | Orientation (mental) | orientation (mental) | National Mental Health Act (1946) |