Quintana considers his poems the first attempts at descriptive poetry in the Castilian language.
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He executed a portrait of Philip IV and worked during the 1620s in a series of portraits of the principal intellectuals and writers of his time, including: Lope de Vega, Francisco de Quevedo, Luis de Góngora, Jose de Valdivieso, Juan Pérez de Montalbán, Juan Ruiz de Alarcón and Francisco de Rioja.