X-Nico

unusual facts about Fructose-bisphosphate aldolase


Fructose-bisphosphate aldolase

Aldolase has also been implicated in many "moonlighting" or non-catalytic functions, based upon its binding affinity for multiple other proteins including F-actin, α-tubulin, light chain dynein, WASP, Band 3 anion exchanger, phospholipase D (PLD2), glucose transporter GLUT4, inositol trisphosphate, V-ATPase and ARNO (a guanine nucleotide exchange factor of ARF6).


Chemical formula

For reasons of structural complexity, there is no condensed chemical formula (or semi-structural formula) that specifies glucose (and there exist many different molecules, for example fructose and mannose, have the same molecular formula Coke 2

Coca-Cola C2, a low-calorie version of Coca-Cola introduced in 2004 using high fructose corn syrup and artificial sweeteners

Fructose 1,6-bisphosphate

Certain neurodegenerative diseases, like Alzheimer's and Parkinson's, have been linked to metal deposits with high iron content, although it is uncertain whether Fenton chemistry plays a substantial role in these diseases, or whether fructose 1,6-bis(phosphate) is capable of mitigating those effects.

Fructose bisphosphatase

Fructose 1,6-bisphosphatase (when the term "Fructose bisphosphatase" is used without qualification, this is more frequently what is meant)

TP53-inducible glycolysis and apoptosis regulator

TIGAR acts as a direct regulator of fructose-2,6-bisphosphate levels and hexokinase 2 activity, and this can lead indirectly to many changes within the cell in a chain of biochemical events.

Turrón

Thirty years ago almost all turrón recipes followed the same specifications, but since the diversification of products there are currently dozens of varieties: chocolate with puffed rice or whole almonds; all kinds of chocolate pralines, with or without liquor, candied fruits or whole nuts; fruit pralines; and even sugarless variations (sweetened with fructose or artificial sweeteners).


see also