The Roman-style facade, overlooking Piazza Verdi, is decorated with stucco and stone from the quarries of Montorfano.
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The main destinations are Genova Brignole, La Spezia Centrale, Pisa Centrale, Roma Termini, Milano Centrale and Torino Porta Nuova.
The main destinations of passengers embarking at the station are Ventimiglia, Genoa and Milano Centrale.