Mathan was born in the village of Kidangannoor, Kerala, India, into an aristocratic family of Tharakans, a noble family in the Kingdom of Travancore.
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Historically, he is also a contemporary of great writers like Mark Twain and Charles Dickens.
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The Malayalam poet and littérateur Mahakavi Ulloor Parameshwaran Iyer (who is considered Kerala's (Malayalam’s) finest poets along with Kumaran Asan, and Vallathol) stated
The Rev. George Mathan Mission Hospital, named after the well-known Malayalam writer and priest, serves as the medical center for an area with no other medical institutions within 16 km of its periphery.
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