The study demonstrated that GAPDH is S-nitrosylated by NO in response to cell stress, which causes it to bind to the protein SIAH1, a ubiquitin ligase.
NADH dehydrogenase | phosphate | Lactate dehydrogenase | Nicotinamide adenine dinucleotide phosphate | Phosphate | British Phosphate Commission | NADPH dehydrogenase | Malate dehydrogenase | Lactate dehydrogenase elevating virus | IMP dehydrogenase | Imidazoleglycerol-phosphate dehydratase | Glucose-6-phosphate dehydrogenase deficiency | Succinate dehydrogenase complex subunit C | Ribose-5-phosphate isomerase deficiency | Pyruvate dehydrogenase | Phosphogluconate dehydrogenase | Phosphate minerals | Phosphate conversion coating | Pentose phosphate pathway | Nauru Phosphate Corporation | N-acetylglucosamine-1-phosphate transferase | methylenetetrahydrofolate dehydrogenase (NADP+) | lithium iron phosphate | lactate dehydrogenase | Glucose-6-phosphate dehydrogenase | Dihydroxyacetone phosphate | Dicalcium phosphate | Corticosteroid 11-beta-dehydrogenase isozyme 2 | Aspartate-semialdehyde dehydrogenase | Aryl-alcohol dehydrogenase |
The oxidative or reductive capacity of the enzyme is regulated by NADH produced by hexose-6-phosphate dehydrogenase (H6PD).
Glucose-6-phosphate dehydrogenase deficiency is very common worldwide, and causes acute hemolytic anemia in the presence of simple infection, ingestion of fava beans, or reaction with certain medicines, antibiotics, antipyretics, and antimalarials.
Modifications to this flux that may improve ethanol production include deleting the GND1 gene, or the ZWF1 gene.