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unusual facts about Granulocyte-colony stimulating factor



Eosinophilic gastroenteritis

In EG cytokines IL-3, IL-5 and granulocyte macrophage colony stimulating factor (GM-CSF) may be behind the recruitement and activation.

Granulocyte macrophage colony-stimulating factor receptor

The granulocyte macrophage colony-stimulating factor receptor is a heterodimer composed of at least two different subunits; an α chain, and a β chain which is also present in the receptors for IL-3 and IL-5.

Juncos, Puerto Rico

Amgen Puerto Rico received FDA approval for bulk manufacturing facilities for Nepogen (Filgrastim), Neulasta (pegfilgrastim), Aranesp and Epogen.

Reticular dysgenesis

The cause of reticular dysgenesis is the inability of granulocyte precursors to form granules secondary to mitochondrial adenylate kinase 2 malfunction.


see also