The Great Stink, or the Big Stink, was a time in the summer of 1858 during which the smell of untreated human waste was very strong in central London.
In 1582 Dutchman Peter Morice leased the northernmost arch of London Bridge and, inside the arch, constructed a waterwheel that pumped water from the Thames to various places in London.
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Because of the miasmatic theory's predominance among scientists, the 1854 discovery by Filippo Pacini of Vibrio cholerae, the bacterium that caused the disease, was ignored until it was rediscovered thirty years later by Robert Koch.
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Henry Moule (1801–1880), English pastor of the Church of England saw a connection between the conditions of hygiene and the expansion of disease; he turned his attention to sanitary science.
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