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He descended, almost directly, from Colonel John Hampden, the patriot; his forebear Sir John Trevor III (1624-72) of Plas Teg, son of Sir John Trevor II of Plas Teg and Trevalun, by Anne daughter of Sir Edmund Hampden of Wendover, had married John Hampden's daughter Ruth, who was his first cousin.
Charles Brand (4th son of Mr. Speaker Brand) of Little Dene, near Lewes, by Alice Emma Sturgis, daughter of Sylvain Van de Weyer.
Brand was the fourth son of Henry Brand, 2nd Viscount Hampden, Governor of New South Wales, and the grandson of Henry Brand, 1st Viscount Hampden, Speaker of the House of Commons.