A designation given by the Borg (the species' name referred to by Star Trek Online as the Undine, though the Hirogen refer to them as 'Fluidians'), Species 8472 has a dense genetic structure, with each cell containing more than a hundred times the genetic material of a human cell because of their triple-helix DNA structure.
Much of the game takes place on the USS Voyager, shooting various alien intruders such as the Borg, Hirogen Hunters, Species 8472 as well as several other alien species from the Star Trek universe.
He has also appeared on television, including seven episodes of Star Trek: Deep Space Nine as the Hupyrian manservant Maihar'du, and two episodes of Star Trek: Voyager as the Hirogen alpha Idrin.