A designation given by the Borg (the species' name referred to by Star Trek Online as the Undine, though the Hirogen refer to them as 'Fluidians'), Species 8472 has a dense genetic structure, with each cell containing more than a hundred times the genetic material of a human cell because of their triple-helix DNA structure.
type species | introduced species | endangered species | Endangered Species Act | On the Origin of Species | Introduced species | List of Uplift Universe species | vulnerable species | Endangered Species | Endangered species | Vulnerable species | Threatened species | threatened species | X-Men: Endangered Species | International Institute for Species Exploration | Type species | List of protected species in Hong Kong | List of Euphorbia species | Grayling (species) | Transmutation of species | Systematics and the Origin of Species | Species problem | Species group | Species | List of Viola species | List of Theraphosidae species | List of freshwater aquarium plant species | Generalist and specialist species | A single-species ruderal community of ''Dittrichia viscosa | Aquatic Species Program |
Much of the game takes place on the USS Voyager, shooting various alien intruders such as the Borg, Hirogen Hunters, Species 8472 as well as several other alien species from the Star Trek universe.