The Institute was founded on 6 September 1943 by a group of local businessmen led by Eugenio Garza Sada, a moneyed heir of a brewing conglomerate who was interested in creating an institution that could provide highly skilled personnel — both university graduates and technicians— to the booming Monterrey corporations of the 1940s.
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Aside from the CETYS experioment and the 150 hectares bought in 1951 for the agricultural program's experimental facilities in nearby Apodaca, Nuevo León, no other expansion outside Monterrey was attempted until 1967, when a school of maritime studies was built in the port of Guaymas, Sonora.
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