Commercial activities in the province are centered on the provincial capital of Borongan City while tourism activities are centered in Guiuan town where Calicoan Island and the historical Homonhon Island are located.
Samar and Leyte, two civil provinces in the Visayan group of the Philippines, which include the islands of Balicuatro, Batac, Biliran, Capul, Daram, Homonhon, Leyte, Manicani, Panaon, Samar and several smaller islands, make up the diocese of Calbayog, a suffragan of the Archdiocese of Manila.