The government proposed to reserve 27% of seats in the premier educational institutions of India like All India Institute of Medical Sciences (AIIMS), Other Medical Colleges, Indian Institutes of Technology (IITs), the Indian Institutes of Management (IIMs), Indian Institute of Science (IISc) and other central institutions of higher education for the OBCs in order to help them gain higher levels of representation in these institutions.
The library maintains Inter-library loan relations with a number of institutions and libraries including IITs, BARC, NITIE, NCST, IISc, IIG, TIFR, IGIDR, TISS and NICT for exchange of books, journals, photocopies and videocassette
At the time of the inception of IISc in 1909, Morris Travers, Sir William Ramsay's co-worker in the discovery of the noble gases, became its first Director.
In 2008 IISC was established as a non-profit organization with offices in Douglas, at the Isle of Man International Business School (IBS).