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With her new position, she allowed the Avengers to disband and be replaced by her 'Americommandos', who arrested the X-Men and other mutants, captured 'illegal' superhumans like Luke Cage and Spider-Man, and arranged for the Fantastic Four to be lost in the Negative Zone, forcing Henry Pym, the Invisible Woman, and the Wasp into retirement, and 'killing' Tony Stark while he was undergoing heart surgery while keeping his brain alive to use his intellect.
In the first series, it was revealed that "Big Brain" is a drone controlled from the Negative Zone, where Sue Storm is held in a kind of stasis.
After Sun's attempt to assassinate the Fantastic Four with Blastaar failed, Dr. Sun reveals himself at last, trapping the Invisible Woman and the Human Torch within the Baxter Building's security system and besting Mister Fantastic and the Thing with H.E.R.B.I.E.'s weapons.
While Fiona tells the simian version of the Fantastic Four about Earth-616, she discovers that in the Marvel Apes reality the cosmic storm that gave the Fantastic Four their powers also gave a human appearance to Susan Storm.
Valeria Richards, daughter of Mister Fantastic and the Invisible Woman (of the Fantastic Four)