Subramanyam Mahadeva Iyer was nominated by his predecessor, Chandrashekarendra Saraswati Swamigal, as his successor and was given the title Jayendra Saraswathi on March 22, 1954.
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Sankara Nethralaya in Chennai, Guwahati, Assam, are formed by him, as well as the Children's Hospital, Hindu Mission Hospital and Tamil Nadu Hospital.
In 1982, Malaysia Hindu Dharma Mamandram was formed by seven founding members with the blessings of His Holiness Jagatguru Sri Jayendra Saraswathi Swamigal of the Kanchi Kamakoti Peetham.
Since its inception, a number of eminent Indians from diverse fields have participated in the activities of the Prime Point Foundation including Sri Jayendra Saraswathi Swamigal, M. S. Swaminathan, T S Krishnamurthy, N Rangachary, T S Raghavan, N Vittal, Yagnaswami Sundara Rajan, and many others.
In 1976 when addressing a group of doctors, Jayendra Saraswathi, the Sankaracharya of the Kanchi Kamakoti Peetam spoke of the need to create a hospital.
He had his first darshana of (i.e. saw) the 69th Kanchi Shankaracharya Jayendra Saraswathi when he was about eight years old.
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He was nominated by his predecessor, Sri Jayendra Saraswathi, as his successor and was given the title Sri Shankara Vijayendra Saraswathi on May 29, 1983 at the early age of 14 years.
Participants included Prof. Samdhong Rinpoche on Buddhism, Diwan Saiyad Zainul Abedin Ali Sahib (Ajmer Sharif) on Islam, Dr. Prabalkant Dutt on non-Catholic Christianity, Swami Jayendra Saraswathi on Hinduism and Dastur Dr. Peshtan Hormazadiar Mirza on Zoroastrianism.