X-Nico

4 unusual facts about John Cade


John Cade

Dr John Frederick Joseph Cade AO (18 January 1912 – 16 November 1980) was an Australian psychiatrist credited with discovering (in 1948) the effects of lithium carbonate as a mood stabilizer in the treatment of bipolar disorder (then known as manic depression).

For his contribution to psychiatry, he was awarded a Kittay International Award in 1974 (with Mogens Schou from Denmark), and he was invited to be a Distinguished Fellow of the American College of Psychiatrists.

Lithia water

In 1949, psychiatrist John Cade discovered the anti-manic effects of lithium ions.

Mogens Schou

The psychopharmacological era began in earnest in 1949, with an article published by John Cade about the observed antimanic action of Lithium in Australia.



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