John L. Griffiths (1855–1914), Consul General of the United States to Britain
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J. Gwyn Griffiths (1911–2004), Welsh poet, Egyptologist and nationalist political activist
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John Calvert Griffiths (born 1931), former Attorney General of Hong Kong and lawyer
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John Griffiths of Us Weekly gave the premiere a negative review, awarding it only two stars.