Porter married, on 8 October 1833, Margaret (d. 7 April 1879, aged 66), eldest daughter of Andrew Marshall, M.D.; Sir Andrew Porter, 1st Baronet was their eldest son.
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On 1 January 1826 he received a unanimous call from the Presbyterian congregation in Carter Lane, Doctors' Commons, London, and was ordained there on 2 March, in succession to John Hoppus His views were Arian, and he became the editor (1826–8) of an Arian monthly, the Christian Moderator; but he was in friendly relations with Thomas Belsham, the leader of those of Joseph Priestley's opinion.
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