In the historical epic 55 Days at Peking, Charlton Heston portrayed Marine Major Matt Lewis, commanding the American Legation Guard in Peking during the Boxer Rebellion.
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In The Wind and the Lion, the fictional Captain Jerome (played by Steve Kanaly) took on Myers' historical role, commanding the Marines dispatched to Tangier during the Perdicaris incident.
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Myers was wounded in the leg by a spear; his attack was claimed by the British Consul, Sir Claude Maxwell MacDonald, as "one of the most successful operations of the siege, as it rendered our position on the wall, which had been precarious, comparatively strong."
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Myers led the detachment of Marines which accompanied the USS Brooklyn to Tangier, Morocco during the Perdicaris incident in 1904.
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Lieutenant John Twiggs Myers, later known for his command during the Boxer Rebellion, marched the Marines through the boathouse and lined them up so that the Spanish and native troops were between the Americans and the ocean.