Leavitt was heavily involved in a series of high-profile anti-slavery cases, including the escape of the slave Basil Dorsey from Maryland into Massachusetts (Leavitt aided Dorsey's passage northward, and members of the extended Leavitt family helped shelter Dorsey in Massachusetts), as well as the La Amistad case, in which enslaved Africans on a Spanish ship rebelled and took control.
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He was the first secretary of the American Temperance Society and co-founder of the New York City Anti-Slavery Society.
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