The Kofa National Wildlife Refuge is located in Arizona in the southwestern United States, northeast of Yuma and southeast of Quartzsite.
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In 1939, after intense lobbying by Frederick Russell Burnham and the Arizona Boy Scouts, President Franklin D. Roosevelt signed a proclamation to establish two desert areas in southwestern Arizona to help preserve the desert bighorn sheep: Cabeza Prieta National Wildlife Refuge and the Kofa National Wildlife Refuge.