X-Nico

unusual facts about La Roche-de-Rame



25 kV AC railway electrification

The first railway to use this system was completed in 1951 by SNCF between Aix-les-Bains and La Roche-sur-Foron in southern France, initially at 20 kV but converted to 25 kV in 1953.

Aimery IV of Thouars

Aimery IV was also lord of La Chaize (near La Roche-sur-Yon), where he built a castle and a church dedicated to St. Nicolas.

Amadora

Siemens and Roche are examples of international companies based in Amadora.

ARF tumor suppressor

The ARF tumor suppressor is a protein that is transcribed from an alternate reading frame of the INK4a/ARF locus (CDKN2A).

Basel Institute for Immunology

The Basel Institute for Immunology (BII) was founded in 1969 as a basic research institute in immunology located at 487 Grenzacherstrasse, Basel, Switzerland on the Rhine River down the street from the main Hoffmann-La Roche campus near the Swiss-German border.

Benserazide

It is used in the management of Parkinson's disease in combination with L-DOPA (levodopa) as co-beneldopa (BAN), under the brand names Madopar in the UK and Prolopa in Canada, both made by Roche.

Benznidazole

Benznidazole (INN, formerly marketed by Hoffman-La Roche under the trade names Rochagan and Radanil) is an antiparasitic medication used in the treatment of Chagas disease.

Canzonissima

The 1962 edition, hosted by Dario Fo and Franca Rame, generated large political controversities due to use of censorship to cut some satirical sketches of Fo; the couple Fo-Rame was eventually fired, and the scandal lead to a long interruption of five years.

Château de Thorens

In the 17th century, the family of Sales, originating from La Roche-sur-Foron and extremely old, saw a fast rise, occupying the highest charges at the House of Savoy in Turin, going from the titles of baron to those of count and, finally, marquis.

Civac

Civac is considered the most important economic development center of the State of Morelos and it accommodates a considerably amount of national and international enterprises such as Roche (formerly Syntex), Unilever, NEC, Baxter International, Alucaps, Givaudan, GlaxoSmithKline, Fibrolub Mexicana, Mycom Mayekawa, along with other 150 companies.

Duchy of Athens

Of Burgundian origin, the dukes of the petty lordly family from La Roche renewed the ancient city of Plato and Aristotle as a courtly European capital of chivalry.

Durance

In the Middle Ages, the county of Forcalquier stretched all along the Durance, from Cavaillon to La Roche-de-Rame, close to Embrun.

Fantôme Brewery

The name of the brewery stems from a legend of the nearby town of La Roche-en-Ardenne, which asserts that the ghost of the long-dead Countess Berthe de La Roche can still be seen walking amidst the ruins of the town's castle.

Freissinières

Freissinières lies in a valley which is the watershed of the Biaisse, which flows into the Durance between La Roche-de-Rame and Saint-Crépin.

Fuld-Gilad-Herring Academy of Competitive Intelligence

The Academy's advisory board includes executives from US-based Intel, Procter and Gamble, Genentech, Blue Cross Blue Shield, Microsoft, Fidelity and Wyeth corporations, as well as Europe-based Shell, Roche, TetraPak and Orange, and Mexico-based Cemex.

Günther von Kluge

When Stauffenberg attempted to assassinate Hitler on July 20, Kluge was Oberbefehlshaber West ("Supreme Field Commander West") with his headquarters in La Roche-Guyon.

HIV/AIDS in Brazil

Brazil invoked the Article 71 for the first time on August 22, 2001, when José Serra, Brazil’s Minister of Health, authorized Far Manguinhos—a Brazilian pharmaceutical company—to produce Nelfinavir, a drug patented by Pfizer but licensed to Roche in the Brazilian market.

Huningue

companies have factories in Huningue, mainly Swiss firms such as Novartis, Ciba, Clariant, Hoffmann-La Roche, Weleda etc.

James Audley

He was afterwards governor of Aquitaine and great seneschal of Poitou, and took part in the capture of the town of La Roche-sur-Yon by Edmund, earl of Cambridge.

Jean-Baptiste Alphonse Karr

His brother Eugène was a talented engineer, and his aunt Carme Karr was a writer, journalist and suffragist in La Roche-Mabile.

Jean-Pierre Travot

He returned to the Vendée in 1807, when he was entrusted with the command of troops newly based in La Roche-sur-Yon, renamed Napoléon as a completely new prefecture within the department.

Jemeppe Castle

These offered little protection against the ruling families of Namur and Luxembourg, who had been fighting to gain control of the territories of Durbuy and La Roche since the 12th century.

La Roche-Guyon

The castle was used as a setting for the medieval segment of a famous Franco-Belgian graphic novel on time travel: Le Piège diabolique (The Diabolical Trap) of the Blake and Mortimer series by Edgar Pierre Jacobs.

Mark A. Hardy

He has received honoraria for lectures in the past from Upjohn, Sangstat, Hoffmann-La Roche, Novartis, Astellas, and Gore.

Novartis Foundation for Sustainable Development

The humanitarian engagement of the Novartis Foundation goes back to the 60s, when the Basel companies Ciba, Geigy, Sandoz, Durand&Huguenin, Hoffmann-La Roche and Lonza founded the Basel Foundation for Developing Countries.

Otto de la Roche

Otto (or Othon) de la Roche (died before 1234) was a Burgundian nobleman from the castle of La Roche-sur-l'Ognon, in the Franche-Comté commune of Rigney, Doubs.

Ro4938581

Ro4938581 is a nootropic drug invented in 2009 by a team working for Hoffmann-La Roche, which acts as a subtype-selective inverse agonist at the benzodiazepine binding site on the receptor.

Roche Institute of Molecular Biology

The Roche Institute of Molecular Biology was created on July 14, 1967 when Jim Burns, then the vice president of research at Hoffman-La Roche, persuaded biochemist Sidney Udenfriend to leave the National Institutes of Health and help him create a basic science institute at the Hoffman-La Roche, Nutley, New Jersey facility.

Sheryll Murray

Murray previously represented Rame as a Cornwall County Councillor and served as Leader of the Conservative Group on Caradon District Council, when a Councillor for Millbrook, prior to her election to Parliament.

Simon de Pury

His mother is Switzerland's leading expert in Ikebana, the Japanese art of flower arranging, and his father was head of the Swiss pharmaceutical company Hoffmann-La Roche.

Tour de Vendée

Tour of Vendée is a single-day road bicycle race held annually in October (Previously May) in the region of Vendée, France, finishing in a circuit inside La Roche-sur-Yon town.

Une sorte de justice

He was sentenced to death on 31 August 1793 and executed by guillotine in the commune of La Roche-Bernard on 5 September 1793.

Voicemail

In the early 1980s, VMX sold voice messaging systems to several large corporations, such as 3M, Kodak, American Express, Intel, Hoffmann–La Roche, Corning Glass, Arco, Shell Canada and Westinghouse.

Waleran I of Luxembourg, Lord of Ligny

Waleram I of Luxembourg (died June 5, 1288 in the Battle of Worringen) was since 1281 Lord of Ligny, Roussy and La Roche.

Wingan Inlet

Wingan Inlet is of historical significance, as it is almost certainly the lagoon, 'one mile north of Rame Head,' where Dr George Bass reputedly became the first European to set foot on the Victorian shoreline on 20 January 1798, during his first expedition south of Sydney to establish the relationship of Tasmania to the Australian mainland, with the encouragement of John Hunter, the Governor of New South Wales.

Yang Cho-cheng

Yang also designed the manufacturing facilities for RCA, Philips, Timex, Texas Instruments in Taiwan; he also designed the manufacturing facilities for pharmaceutical companies such as Eli Lilly and Company and Roche.


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