He became a Knights Hospitaller and was the Order's governor of the island of Lango when Rhodes fell to the Ottomans on New Year's Day 1523, and was still there in 1534 when he received the news of his election to the office of Grand Master of the Order, to succeed Philippe Villiers de L'Isle-Adam at Malta.
During the civil war in Uganda between the UNLA (which was now the national army) and Yoweri Museveni's National Resistance Army, president Milton Obote alienated much of the Acholi-dominated officer corps, including Olara-Okello and General Tito Okello, by appointing his fellow ethnic Lango, Brigadier Smith Opon Acak, as army Chief of Staff.
Further west, Lopa/Lafon, Torit and Ikwoto counties are inhabited by the Otuho, Lopit, Lango, Pari, and Tenet people who inhabit a portion of Lopit hills after they split from Didinga and Murle early in 19th century and Lokoya of Lowoi.
The income generated by cotton sales made the Buganda kingdom relatively prosperous, compared with the rest of colonial Uganda, although before World War I cotton was also being grown in the eastern regions of Busoga, Lango, and Teso.