With Langston Hughes's epic poem for a libretto, Karpman's work exhibited an eclectic musical mix.
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Karpman’s score for "Ask Your Mama: 12 Moods for Jazz" premiered at Carnegie Hall on March 16, 2009 with performances by Jessye Norman, Cassandra Wilson, The Roots, and the Orchestra of St. Luke's conducted by George Manahan.
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Karpman worked with John Harbison at the Tanglewood Music Center, and attended Aspen Music School and the Ecole des Arts Americaines, where she worked with Nadia Boulanger.
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