Registration, Evaluation, Authorisation and Restriction of Chemicals | MHC class I | Restriction enzyme | MHC Krylya Sovetov | MHC class II | Gonakudzingwa Restriction Camp | Restriction digest | MHC Class II | MHC Class I | DpnII restriction endonuclease family |
That observation, called MHC restriction, led to a conundrum; namely, that the ability of a T cell to recognize foreign antigen also required that it recognize "self." With Paul M. Allen, Ph.D., the Robert L. Kroc Professor at Washington University School of Medicine, Unanue discovered that peptides from foreign antigens were bound to a group of molecules known as the major histocompatibility complex (MHC).