From 1907, Castione-Arbedo station was the principal interchange point between the Gotthard railway and the Bellinzona–Mesocco railway (BM), a metre gauge railway linking Bellinzona and various communities in the Val Mesolcina as far as Mesocco.
San Giacomo Filippo borders the following municipalities: Campodolcino, Chiavenna, Menarola, Mese, Mesocco (Switzerland), Piuro, Soazza (Switzerland).