In 116 AD, the Roman emperor Trajan invaded the Parthian empire and conquered all the way to Babylon.
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Naram-Sin quickly destroyed and dispersed the Sumerian rebels and also went on a vast campaign of conquest, taking his armies to Lebanon, Syria and Israel, and then to Egypt.
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The city's status as residence of the Eastern Roman Emperor made it into the premier city in all of the Eastern Roman colonies in the Balkans, Syria, Jordan, Israel, Lebanon, Cyprus, Egypt, and part of present day Libya.
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After some years of peace, Sargon waged wars against his rival Elam, and then launched a separate attack on Syria and Lebanon.
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Elements of the Timar system however can be seen to have their origins in Pre-Islamic antiquity (Ancient Middle Eastern Empires, Rome, Byzantium, and Pre-Islamic Iran).