In the tumultuous atmosphere of the revolt against Ferrante, the Aragonese King of Naples by the local lords who supported the claims of the House of Anjou, which broke out anew in 1460, Francesco Sforza had induced the Pope, Pius II to support Ferrante in the Neapolitan War of 1460-61.
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Initially he followed a military career, taking part in the Angevin-Neapolitan war.