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In 1915, the Neighborhood Playhouse, one of the first "Little Theatres", was created by the sisters Alice and Irene Lewisohn at the corner of Grand and Pitt Streets, offering classical drama for the people of the area.
A graduate of Yale University, Mr. Alfieri began his professional career in New York City, where he studied with Sanford Meisner at the Neighborhood Playhouse.
She studied in advanced private classes in New York City with Sandy Meisner (Neighborhood Playhouse), Mira Rostova (Moscow Art Theatre), Wynn Handmann (American Place), and Lloyd Richards (Yale University Drama School).
Playwright Horton Foote met actor Robert Duvall at Neighborhood Playhouse when Duvall starred in a 1957 production of Foote's play, The Midnight Caller.