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The film is based on a book by Nicholas Monsarrat that nearly had Helen Keller's co-workers suing for libel due to perceived parallels between Helen's story and Esther's.
It is an often quoted line, also appearing in Nicholas Monsarrat's 1951 novel, The Cruel Sea, where it is used to underscore the blunt tragedies of war- the novel cuts off a side story of a romance, and the protagonist quotes the line, bitterly, as the main storyline resumes.