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3 unusual facts about Paternal age effect


Paternal age effect

In 2012, two 96-year-old men, Nanu Ram Jogi and Ramjit Raghav, both from India, claimed to have fathered children that year.

In 1912, Wilhelm Weinberg, a German physician, was the first person to hypothesize that non-inherited cases of achondroplasia could be more common in last-born children than in children born earlier to the same set of parents.

In 1933, Lionel Penrose analyzed data for 727 children in 150 families and found no paternal age effect for the risk of Down syndrome after controlling for the maternal age effect.



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